Antibodies kill cancer cells - new cancer treatment?

It has been known that antibodies can be used to tag cancer cells and mobilize the disease fighting cells of the immune system to attack and kill cancer cells. Now according to a report in the Journal of Clinical Investigations by researchers of the University of Nottingham and the University of Manchester, the antibodies it selves can attack and destroy directly cancer cells.

The antibody works as follows. It attaches to a cancer cell and trigger lysosomes (small acid-containing sacs) within the cell to bloat up and burst in the process releasing their deadly content leading to the death of the cell. According to researcher Dr. Mark Cragg, the findings throws up the tantalizing possibility of applying this knowledge of how antibodies trigger cell death to come up with new effective treatments for cancer.

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